Department Facilities and locationsResearch platformsOptical microscopy

Optical microscopy

SAMPLE PREPARATION

• Embedding and sectioning of paraffin-embedded tissue samples
• Embedding and sectioning of frozen tissue samples
• Histological and histochemical stainings
• Immunohistochemistry
• Immunofluorescence

Semi-automated paraffin embedding system	Microtome workstations for the preparation of thin paraffin-embedded sections		Cryostat microtome for the preparation of thin frozen sections

SAMPLE ANALYSIS

• Visible light optical microscopy
• UV light optical microscopy for fluorescence
• Digital microphotography and image analysis (ImageJ; AIVIA software): linear, area, and optical density measurements, etc.
• Histological stainings
• Histochemistry
• Immunohistochemistry
• Immunofluorescence
• Whole-slide imaging of microscopic specimens for research and diagnostics
• Morphometry

Visible light optical microscopes with digital photography and image analysis systems	UV light fluorescence microscopes with digital photography and image analysis systems		Inverted microscope for visible light and fluorescence analysis of cell cultures with digital imaging system

GRUNDIUM OCUS®40 brightfield optical microscopy slide scanner. Thanks to the excellent resolving power, chromatic aberration correction, and complete flatness of its objective lens (Olympus), it enables the high-resolution acquisition of whole-slide microscopic specimens with high color fidelity and a digital magnification of up to 800% without losing image quality. It allows for the real-time cloud archiving of high-resolution images and remote sharing via the internet with the user for research and diagnostic purposes.